Publicaciones (últimos 10 años) imagePublicaciones (últimos 10 años) image

  • Inostroza M, Utrera A, Garcia-Herrera CM, Rivera E, Celentano D, Herrera EA. Analysis of the geometrical influence of ring-opening samples on arterial circumferential residual stress reconstruction. Front Bioeng Biotech (Biomechanics) 2023 [ahead print] IF: 6,07.

  • González-Candia A, Candia AA, Arias PV, Paz AA, Herrera EA*, Castillo RL*. Chronic intermittent hypobaric hypoxia induces cardiovascular dysfunction in a high-altitude working shift model. Life Sci. 2023 [ahead print] IF: 6,78. 

  • Candia AA, Jiménez T, Navarrete Á, Beñaldo F, Silva P, García-Herrera C, Sferruzzi-Perri AN, Krause BJ, González-Candia A*, Herrera EA*. Developmental Ultrasound Characteristics in Guinea Pigs: Similarities with Human Pregnancy. Vet Sci. 2023 Feb 10;10(2):144. doi: 10.3390/vetsci10020144. IF: 2,314. 

  • Kane AD*, Herrera EA*, Niu Y, Camm EJ, Allison BJ, Tijsseling D, Lusby C, Derks JB, Brain KL, Bronckers IM, Cross CM, Berends L, Giussani DA. Combined Statin and Glucocorticoid Therapy for the Safer Treatment of Preterm Birth. Hypertension. 2023 Feb 1. doi: 10.1161/HYPERTENSIONAHA.122.19647. IF: 10,001. 

  • Laubrie JD, Bezmalinovic A, García-Herrera CM, Celentano DJ, Herrera EA, Avril S, Llanos AJ. Hyperelastic and damage properties of the hypoxic aorta treated with Cinaciguat. J Biomechanics. 2023, doi: 10.1016/j.jbiomech.2023.111457. IF: 3,055.


  • González-Candia A, Candia AA, Paz A, Mobarec F, Urbina-Varela R, del Campo A, Herrera EA, Castillo RL. Cardioprotective Antioxidant and Anti-Inflammatory Mechanisms Induced by Intermittent Hypobaric Hypoxia. Antioxidants, 11(6): 10.3390/antiox11061043, 2022. IF: 6,313. 

  • Beñaldo FA, Araya-Quijada C, Ebensperger G, Herrera EA, Reyes RV, Moraga FA, Riquelme AN, González-Candia A, Valenzuela GJ, Seron-Ferre M, Llanos AJ. Cinaciguat (BAY-582667) modifies the cardiopulmonary and systemic circulations in chronically hypoxic and pulmonary hypertensive neonatal lambs in the Alto Andino. Front Physiol. 13:864010, 2022. doi: 10.3389/fphys.2022.864010. IF:4,566

  • Sandoval I, Véliz R, Sepúlveda-Martínez A, Candia AA, Herrera EA. Utilidad de la Ecografía Doppler en el Diagnóstico, Pronóstico y Manejo de la Restricción del Crecimiento Fetal: Situación en Chile (Usefulness of Doppler Ultrasound for the Diagnosis, Prognosis and Management of Fetal Growth Restriction: Situation in Chile). Revista Chilena de Obstetricia y Ginecología 0011/21; 2022. 

  • Utrera A, Navarrete A, González‑Candia A, García‑Herrera C, Herrera EA. Biomechanical and structural responses of the aorta to intermittent hypobaric hypoxia in a rat model. Sci Rep. 12(1):3790, 2022. IF: 4,379.

  • Candia AA, Arias PV, González-Candia C, Navarrete A, Ebensperger G, Reyes RV, Llanos AJ, González-Candia A, Herrera EA. Melatonin treatment during chronic hypoxic gestation improves neonatal cerebrovascular function. Vasc Pharmacol. 2022:106971. IF: 5,773. 

  • Castillo-Galán S, Parrau D, Hernández I, Quezada S, Díaz M, Ebensperger G, Herrera EA, Moraga FA, Iturriaga R, Llanos AJ, Reyes RV. The action of 2-AminoethyldiPhenyl Borinate on the pulmonary arterial hypertension and remodeling of high-altitude hypoxemic lambs. Front Physiol. 12:765281, 2022. IF: 4,566.

  • McGillick EV, Orgeig S, Allison BJ, Brain KL, Niu Y, Itani N, Skeffington KL, Kane AD, Herrera EA, Morrison JL, Giussani DA. Molecular regulation of lung maturation in near-term fetal sheep by maternal daily Vitamin C treatment in late gestation. Pediatr Res. 91 (4): 828-838, 2022. IF: 2,88.

  • González-Candia A, Herrera EA. High altitude pregnancies and vascular dysfunction: observations from Latin American studies. Front Physiol. 12:786038, 2021. doi: 10.3389/fphys.2021.786038. IF: 4,566. 

  • Hansell JA, Richter HG, Camm EJ, Herrera EA, Blanco CE, Villamor E, Patey OV, Lock MC, Trafford AW, Galli GLJ, Giussani DA. Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy. J Pineal Res. e12766, 2021. IF: 15,2.

  • Herrera EA, González-Candia A. Gestational hypoxia and blood-brain barrier permeability: early origins of cerebrovascular dysfunction induced by epigenetic mechanisms. Front Physiol. 12:717550, 2021. IF: 4,566.

  • González-Candia A, Arias PV, Aguilar, SA, Figueroa EG, Reyes RV, Ebensperger G, Llanos AJ, Herrera EA. Melatonin reduces oxidative stress in the right ventricle of newborn sheep gestated under chronic hypoxia. Antioxidants. 10(11):1658, 2021. IF: 6,313. 

  • Rivera E, Canales C, Pacheco M, García-Herrera C, Macias D, Celentano DJ, Herrera EA. Biomechanical characterization of the passive response of the thoracic aorta in chronic hypoxic newborn lambs using an evolutionary strategy. Sci Rep. 11(1):13875, 2021. IF: 3,99

  • Figueroa EG, González-Candia A, Caballero-Román A, Fornaguera C, Escribano-Ferrer E, García-Celma MJ, Herrera EA. Blood-brain barrier dysfunction in hemorrhagic transformation: a therapeutic opportunity for a novel melatonin nanocarrier in the ischemic brain. J Neurophysiol. 125(6):2025-2033, 2021. IF: 2,23. 

  • Figueroa EG, González-Candia A, Villanueva CA, Ebensperger G, Reyes RV, Llanos AJ, Herrera EA. Beneficial effects of melatonin on prostanoids pathways in pulmonary hypertensive neonates. Vasc Pharmacol. 138:106853, 2021. IF: 3,64. 

  • García–Herrera CM, Cuevas AA, Celentano DJ, Navarrete A, Aranda P, Herrera EA, Uribe S. Analysis of the passive biomechanical behavior of a sheep-specific aortic artery in pulsatile flow conditions. Comput Methods Biomech Biomed Engin. 24(11):1228-1241, 2021. IF: 1,502. DOI: 10.1080/10255842.2021.1872549


  • Navarrete A, Chen Z, Aranda P, Poblete D, Garcia-Herrera C, González-Candia A, Beñaldo FA, Ebensperger G, Reyes RV, Herrera EA, Llanos AJ. Study of the effect of treatment with Atrial Natriuretic Peptide (ANP) and Cinaciguat in chronic hypoxic neonatal lambs on residual strain and microstructure of the arteries. Front Bioeng Biotechnol. 8: 590488, 2020. IF: 4,21.

  • Rivera E, García-Herrera C, González-Candia A, Celentano DJ, Herrera EA. Effects of melatonin on the passive mechanical response of arteries in chronic hypoxic newborn lambs. J Mech Behav Biomed Mater. 112: 104013, 2020. IF: 3,37.

  • Allison B, Brain K, Niu Y, Kane A, Herrera EA, Thakor A, Botting K, Cross C, Itani N, Shaw C, Skeffington K, Beck C, Giussani DA. Altered Cardiovascular Defense to Hypotensive Stress in the Chronically Hypoxic Fetus. Hypertension. 76(4): 1195-1207, 2020. IF: 7,02.

  • Bezmalinovic A, Rivera E, García-Herrera C, Celentano D, González-Candia A, Herrera EA. Caracterización del daño mecánico de la aorta en condición de hipoxia: Modelamiento y simulación numérica de un ensayo de presurización. Materia (Rio J.) 26 (01), 2021. IF: 0,40.

  • Reyes RV, Herrera EA, Ebensperger G, Sanhueza EM, Giussani DA, Llanos AJ. Perinatal cardiopulmonary adaptation to the thin air of the Alto Andino by a native Altiplano dweller, the llama. J Appl Physiol 129(1): 152-161, 2020. IF: 3,14. 

  • González-Candia A, Candia AA, Ebensperger G, Reyes RV, Llanos AJ, Herrera EA. The newborn sheep translational model for pulmonary arterial hypertension of the neonate at high-altitude. J Dev Orig Health Dis. 11(5): 452-463, 2020. IF: 2,34. 

  • Herrera EA, González-Candia A. Comment on Melatonin as a potential adjuvant treatment for COVID-19. Life Sci. 253: 117739, 2020. IF: 3,448. 

  • Valenzuela OA, Jellyman JK, Allen V, Niu Y, Holdstock NB, Forhead AJ, Giussani DA, Fowden AL, Herrera EA. Neonatal glucocorticoid overexposure alters cardiovascular function in young adult horses in a sex-linked manner. J Dev Orig Health Dis. 3:1-10, 2020. IF: 2,34.

  • Tadich TA, de Freslón I, Gallo C, Zúñiga JM, Vargas R, Torres CG, Tadich N, Gimpel J, Martinez C, Sandoval D, Enríquez R, Alfaro J, Muñoz P, Paredes R, Erranz B, Carvacho I, Mezzano M, Herrera EA. Incorporation of bioethical standards for the generation of high quality scientific knowledge from research in wildlife: Science with conscience. Gayana. 84 (1): 68-74, 2020. IF: 0.406.

  • González-Candia A, Candia AA, Figueroa EG, Feixes E, González-Candia C, Aguilar SA, Ebensperger G, Reyes RV, Llanos AJ, Herrera EA. Melatonin long lasting beneficial effects on pulmonary vascular reactivity and redox balance in chronic hypoxic ovine neonates. J Pineal Res. 68 (1): e12613, 2020. IF: 15.22 


  • Conei D, del Sol M, Muñoz Cofré R, Escobar Cabello M, Saavedra H, Herrera EA, Garcia-Herrera CM. Morphological and mechancal effects in Sprague Dawley rats subjected to hypoxia cycles. Int J Morphol. 37(3): 908-911, 2019. IF: 0.21

  • Beñaldo FA, Llanos AJ, Araya-Quijada C, Rojas A, González-Candia A, Herrera EA, Ebensperger G, Cabello G, Valenzuela GJ, Serón-Ferré M. Effects of Melatonin on the Defense to Acute Hypoxia in Newborn Lambs. Front Endocrinol (Lausanne). 10:433, 2019. IF: 3.63

  • Paz AA, Arenas GA, Castillo-Galán S, Peñaloza E, Cáceres-Rojas G, Suazo J, Herrera EA, Krause BJ. Premature Vascular Aging in Guinea Pigs Affected by Fetal Growth Restriction. Int J Mol Sci. 20(14). pii: E3474, 2019. IF: 4.18

  • Krause BJ*, Peñaloza E, Candia A, Cañas D, Hernández C, Arenas A, Peralta-Scholz MJ, Valenzuela R, García-Herrera C, Herrera EA*. Adult vascular dysfunction in fetal growth restricted guinea pigs is associated with a neonate-adult switching in Nos3 DNA methylation. Acta Physiol. E13328, 2019. IF: 5.93 

  • Herrera EA, Ebensperger G, Hernández I, Sanhueza EM, Llanos AJ, Reyes RV. The role of nitric oxide signaling in pulmonary circulation of high- and low-altitude newborn sheep under basal and acute hypoxic conditions. Nitric Oxide. 89: 71-80, 2019. IF: 4.367

  • Aguilar SA, Arias PV, Canquil I, Ebensperger G, Llanos AJ, Reyes RV, González-Candia A, Herrera EA. El tratamiento postnatal con melatonina modula la expresión de agentes prostanoides en pulmón de neonatos de oveja con hipertensión pulmonar. Rev Med Chil. 147(3):281-288, 2019. IF: 0.582 

  • González-Candia A, Veliz M, Carrasco-Pozo C, Castillo RL, Cárdenas JC, Ebensperger G, Reyes RV, Llanos AJ, Herrera EA. Antenatal melatonin modulates an enhanced antioxidant/pro-oxidant ratio in pulmonary hypertensive newborn sheep. Redox Biol. 22:101128, 2019. doi: 10.1016/j.redox.2019.101128. IF: 7.16 

  • Brain KL, Allison BJ, Niu Y, Cross CM, Itani N, Kane AD, Herrera EA, Skeffington KL, Botting KJ, Giussani DA. Intervention against hypertension in the next generation programmed by developmental hypoxia. PLoS Biol. 2019;17(1):e2006552. doi: 10.1371/journal.pbio.2006552. IF: 9.16

  •  Lopez-Tello J, Jimenez-Martinez MA, Herrera EA, Krause BJ, Sferruzzi-Perri AN. Progressive uterine artery occlusion in the Guinea pig leads to defects in placental structure that relate to fetal growth. Placenta. 2018; 72-73:36-40. doi: 10.1016/j.placenta.2018.10.003.  IF: 3.01


  • Morrison JL, Berry MJ, Botting KJ, Darby JRT, Frasch MG, Gatford KL, Giussani DA, Gray CL, Harding R, Herrera EA, Kemp MW, Lock MC, McMillen IC, Moss TJ, Musk GC, Oliver MH, Regnault TRH, Roberts CT, Soo JY, Tellam RL. Improving pregnancy outcomes in humans through studies in sheep. Am J Physiol Regul Integr Comp Physiol. Dec 1;315(6):R1123-R1153, 2018. doi: 10.1152/ajpregu.00391.2017. IF: 3.17

  • Cañas D, García-Herrera CM, Herrera EA, Celentano DJ, Krause BJ. Mechanical characterization of arteries affected by fetal growth restriction in guinea pigs (Cavia porcellus). J Mech Behav Biomed Mater. 88: 92-101. 2018. IF: 3.57

  • Reyes RV, Castillo-Galán SA, Hernandez I, Herrera EA, Ebensperger G, Llanos AJ. Revisiting the role of TRP, ORAI and ASIC channels in the pulmonary arterial response to hypoxia. Front Physiol. 9:486. doi: 10.3389/fphys.2018.00486. eCollection 2018, 2018. IF: 4.13 

  • Morrison JL, Botting KJ, Darby JRT, David AL, Dyson RM, Gatford KL, Gray C, Herrera EA, Hirst JJ, Kim B, Kind KL, Krause BJ, Matthews SG, Palliser HK, Regnault TRH, Richardson BS, Sasaki A, Thompson LP, Berry M. Guinea pig models for translation of DOHaD into the clinic. J Physiol. 596(23):5535-5569, 2018. doi: 10.1113/JP274948. IF: 5.04 

  • Astorga CA,  Gonzalez-Candia A,  Candia AA,  Figueroa EG,  Cañas D,  Ebensperger G, Reyes RV, Llanos AJ, Herrera EA. Melatonin decreases pulmonary vascular remodelling and oxygen sensitivity in pulmonary hypertensive newborn lambs. Front Physiol. 9:185. doi: 10.3389/fphys.2018.00185. eCollection 2018. IF: 4.13. 

  • Reyes RV, Díaz M, Ebensperger G, Herrera EA, Quezada SA, Hernandez I, Sanhueza EM, Parer JT, Giussani DA, Llanos AJ. The role of nitric oxide signaling in the cardiopulmonary response to hypoxia in high- and lowland newborn llamas. J Physiol. 596(23):5907-5923, 2018. doi: 10.1113/JP274340. IF: 5,04

  • Aguilar M, González-Candia A, Rodríguez J, Carrasco-Pozo C, Cañas D, García C, Herrera EA*, Castillo RL*. Mechanisms of cardiovascular protection associated with intermittent hypobaric hypoxia exposure in a rat model: role of oxidative stress. Int J Mol Sci. 19(2). pii: E366. doi: 10.3390/ijms19020366, 2018. IF: 3.68. 

  • Salas X, Mancilla V, Zapata D, González-Candia A, Herrera EA. Efecto de la administración prenatal de melatonina en pulmones de neonatos de oveja crónicamente hipóxicos. Rev. ANACEM 2017; 11(2). 

  • Castillo RL, Herrera EA, González-Candia A, Reyes-Farías M, De la Jara N, Peña J, Carrasco-Pozo C. Quercetin prevents diastolic dysfunction induced by a high cholesterol diet: role of oxidative stress and bioenergetics in hyperglycemic rats. Oxid Med Cell Longev. 2018:7239123. doi: 10.1155/2018/7239123. eCollection 2018. IF: 4.593


  • Kosanovic D, Herrera EA, Sydykov A, Orfanos SE, Agha EE. Pulmonary Hypertension due to Lung Diseases and/or Hypoxia: What Do We Actually Know? Can Respir J. 2017:9598089. doi: 10.1155/2017/9598089, 2017. IF: 1,153 

  • McGillick EV, Orgeig S, Allison BJ, Brain K, Niu Y, Itani N, Skeffington KL, Kane AD, Herrera EA, Giussani DA, Morrison JL. Maternal chronic hypoxia increases expression of genes regulating lung liquid movement and surfactant maturation in male fetuses in late gestation. J Physiol. 595(13):4329-4350, 2017. IF: 5,04

  •  Cañas D, Herrera EA, García-Herrera C, Celentano D, Krause BJ. Fetal growth restriction induces heterogeneous effects on vascular biomechanical and functional properties in guinea pigs (Cavia porcellus). Front Physiol. 8:144, 2017. IF: 4,03

  • Herrera EA, Cifuentes-Zúñiga F, Figueroa E, Villanueva C, Hernández C, Alegría R, Arroyo V, Peñaloza E, Farías M, Uauy R, Casanello P, Krause BJ. N-acetyl cysteine, a glutathione precursor, reverts vascular dysfunction and endothelial epigenetic programming in intrauterine growth restricted guinea pigs. J Physiol. 595(4):1077-1092, 2017. IF: 5,04


  • Castillo-Galán S, Quezada S, Moraga FA, Ebensperger G, Herrera EA, Beñaldo F, Hernandez I, Ebensperger R, Ramirez S, Llanos AJ, Reyes RV. 2-aminoethyldiphenylborinate modifies the pulmonary circulation in pulmonary hypertensive newborn lambs with partial gestation at high altitude. Am J Physiol Lung Cell Mol Physiol. 311(4):L788-L799, 2016. doi: 10.1152/ajplung.00230.2016. IF: 4.72

  • Garcia-Herrera CM, Herrera EA, Celentano DJ. Modelling and numerical simulation of the in-vivo mechanical response of the ascendingaortic aneurysm in Marfan's syndrome. Med Biol Eng Comput.(MBEC) 55(3):419-428, 2016. IF: 1,73

  • Kane AD, Niu Y, Herrera EA, Morton AJ, Giussani DA. Impaired nitric oxide mediated vasodilation in the peripheral circulation in the R6/2 mouse model of Huntington's disease. Sci Rep. 6:25979, 2016. IF: 5,58

  • Allison BJ, Brain KL, Niu Y, Kane AD, Herrera EA, Thakor AS, Botting KJ, Cross CM, Itani N, Skeffington KL, Beck C, Giussani DA. Fetal in vivo continuous cardiovascular function during chronic hypoxia. J Physiol. 594(5):1247-64, 2016. doi: 10.1113/JP271091. IF: 5,04 Journal cover image

  • Lopez NC, Ebensperger G, Herrera EA, Reyes RV, Calaf G, Cabello G, Moraga FA, Benaldo FA, Diaz M, Parer JT, Llanos AJ. Role of the RHOA/ROCK pathway in high-altitude associated neonatal pulmonary hypertension in lambs. Am J Physiol Regul Integr Comp Physiol. 310(11):R1053-63, 2016. IF: 3,11

  • González-Candia A, Veliz M, Araya C, Quezada S, Ebensperger G, Serón-Ferré M, Reyes RV, Llanos AJ, Herrera EA. Potential adverse effects of antenatal melatonin as a treatment for intrauterine growth restriction: findings in pregnant sheep. Am J Obstet Gynecol. 215 (2): 245.e1-7, 2016.  IF: 4,70. 

  • Herrera EA, Alegría R, Farias M, Díaz-López F, Hernández C, Uauy R, Regnault TRH, Casanello P, Krause BJ. Assessment of in vivo fetal growth and placental vascular function in a novel IUGR model of progressive uterine artery occlusion in guinea pigs. J Physiol. 594(6):1553-61, 2016. IF: 5,04. 

  • Herrera EA, Rojas RT, Krause BJ, Ebensperger G, Reyes RV, Giussani DA, Parer JT, Llanos AJ. Cardiovascular function in term fetal sheep conceived, gestated and studied in the hypobaric hypoxia of the Andean Altiplano. J Physiol. 594(5):1231-45, 2016 [Joseph Barcroft Special Issue]. IF: 5,04

  • Farías JF*, Herrera EA*, Carrasco-Pozo C, Sotomayor-Zárate R, Cruz G, Morales P, Castillo RL. Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress. Pharmacol Ther. 158:1–23, 2016. IF: 10,4. 

  • Krause BJ, Herrera EA, Díaz-López FA, Farías M, Uauy R, Casanello P. Pre-gestational overweight in guinea pig sows induces foetal vascular dysfunction and increased rate of large and small foetuses. J DOHaD. 7 (3): 237-243: 2016. IF: 2,2


  • Brain KL, Allison BJ, Niu Y, Cross CM, Itani N, Kane AD, Herrera EA, Giussani DA. Induction of Controlled Hypoxic Pregnancy in Large Mammalian Species. Physiol Rep. 3(12): pii e12614, 2015.

  •  Herrera EA, Ebensperger G, Reyes RV, Llanos AJ. The study of high altitude pulmonary hypertension at the Chilean Andean Altiplano. Perspective Learners` Corner. PVRI Chronicle 2(2): 49-52, 2015.  

  • Herrera EA, Farías JG, Ebensperger G, Reyes RV, Llanos AJ, Castillo RL. Pharmacological approaches in either intermittent or permanent hypoxia: A tale of two exposures. Pharmacol Res. 101:94-101, 2015. IF: 4,41 

  • Thakor AS, Allison BJ, Niu Y, Botting KJ, Serón-Ferré M, Herrera EA, Giussani DA. Melatonin induces redox modulation of the fetal defense to acute hypoxia. J Pineal Res. 59(1): 80-90, 2015. doi: 10.1111/jpi.12242 IF: 9,6

  • Torres F, Gonzalez-Candia A, Montt C, Ebensperger G, Chubretovic M, Serón-Ferré M, Reyes RV, Llanos AJ, Herrera EA. Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep. J Pineal Res. 58(3):362-73, 2015. doi: 10.1111/jpi.12222.  IF: 9,6. 

  • Herrera EA, Farias JG, González-Candia A, Short S, Carrasco-Pozo C, Castillo RL. Ω3 supplementation and intermittent hypobaric hypoxia induce cardioprotection enhacing antioxidant mechanisms in adult rats. Marine Drugs - Marine Functional Food Products - Cardiovascular Diseases. 13(2):838-60, 2015. doi: 10.3390/md13020838. IF: 3,9

  • Seron-Ferre M, Reynolds H, Mendez NA, Mondaca M, Valenzuela F, Ebensperger R, Valenzuela GJ, Herrera EA, Llanos AJ, Torres-Farfan C. Impact of maternal melatonin suppression on amount and functionality of brown adipose tissue (BAT) in the newborn sheep. Front Endocrinol (Lausanne). 5:232, 2015. doi: 10.3389/fendo.2014.00232. eCollection 2014. IF: 3.519

  • Castillo R, Farias JG, Herrera EA, Alvarez PI, Short SE, Tapia L, Carrasco R, Sotomayor R. Effects of Chronic Intermittent Hypoxia and Polyunsaturated Fatty Acids on Infarct Size and Oxidative Stress Markers in Cardiac Ischemia Reperfusion. Exp Clin Cardiol. 20(8): 3833-3858, 2014. IF: 1,1

  • Herrera EA, Krause BJ, Ebensperger G, Reyes RV, Casanello P, Parra-Cordero M, Llanos AJ. The placental pursuit for an adequate oxidant balance between the mother and the fetus. Front Pharmacol. 5:149, 2014. doi: 10.3389/fphar.2014.00149. eCollection. IF: 3,8 Review. 

  • Herrera EA, Macchiavello R, Montt C, Ebensperger G, Díaz M, Ramírez S, Parer JT, Serón-Ferré M, Reyes RV, Llanos AJ. Melatonin improves cerebrovascular function and decreases oxidative stress in chronically hypoxic lambs. J Pineal Res. 57:33–42, 2014. doi: 10.1111/jpi.12141.  IF: 9,6. 

  • Casanello P, Schneider D, Herrera EA, Uauy R, Krause BJ. Endothelial heterogeneity in the umbilico-placental unit: DNA methylation as an innuendo of epigenetic diversity. Front Pharmacol. 5:49, 2014. doi:10.3389/fphar.2014.00049. IF: 3,8 Review

  • Kane AD, Hansell J, Herrera EA, Allison B, Niu Y, Brain K, Kaandorp J, Derks J, Giussani DA. Xanthine oxidase and the fetal cardiovascular defence to hypoxia in late gestation ovine pregnancy. J Physiol. 592(Pt 3):475-89, 2014. IF: 5,04 Paper seleccionado como de alto impacto y comentado en Perspectives.

  • Niu Y, Herrera EA, Evans RD, Giussani DA. Antioxidant treatment improves neonatal survival and prevents impaired cardiac function at adulthood following neonatal glucocorticoid therapy. J Physiol 591(Pt 20):5083-93, 2013. IF: 5,04 Paper seleccionado como de alto impacto y comentado en Perspectives.

  • Kane AD, Herrera EA, Camm EJ, Giussani DA. Vitamin C prevents intrauterine programming of in vivo cardiovascular dysfunction in the rat. Circulation J. 77(10):2604-11, 2013. IF: 3,94

  • Tijsseling D, Camm EJ, Richter HG, Herrera EA, Kane AD, Niu Y, Cross CM, de Vries WB, Derks JB, Giussani DA. Statins prevent adverse effects of postnatal glucocorticoid therapy on the developing brain in rats. Pediatr Res. 74(6):639-45, 2013. IF: 2,31

  • Parrau D, Ebensperger G, Herrera EA, Moraga FA, Riquelme RA, Ulloa CE, Rojas RT, Silva P, Hernandez I, Ferrada J, Diaz M, Parer JT, Cabello G, Llanos AJ, Reyes RV. Store operated channels in the pulmonary circulation of high and low altitude neonatal lambs. Am J Physiol Lung Cell Mol Physiol. 304(8): L540-L548, 2013. IF: 4,08

  • Cindrova-Davies T*, Herrera EA*, Niu Y, Kingdom J, Giussani DA, Burton GJ. Reduced cystathionine γ-lyase and increased miR-21 are associated with increased vascular resistance in growth-restricted pregnancies: hydrogen sulfide as a placental vasodilator. Am J Pathol. 182(4): 1448-1458, 2013. IF: 5,07 


  • Herrera EA, Salinas CE, Blanco CE, Villena M, Giussani DA. High altitude hypoxia and blood pressure dysregulation in adult chickens. J DOHaD. 4(1): 29-36, 2012. IF: 1,1

  • Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Cabello G, Díaz M, Giussani DA, Parer JT.  The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude. Respir Physiol Neurobiol. 184: 186-191, 2012. IF: 1,97 Review

  • Herrera EA, Kane AD, Hansell JA, Thakor AS, Allison BJ, Niu Y, Giussani DA. A role for xanthine oxidase in the control of fetal cardiovascular function in late gestation sheep. J Physiol. 590(8): 1825-1837, 2012. IF: 5,04 Paper seleccionado como Editor´s choice de abril 2012 & comentado por Peebles D. J Physiol. 590(8): 1773, 2012.

  • Giussani DA, Camm EJ, Niu Y, Richter HG, Blanco CE, Gottschalk R, Zachary Blake E, Horder KA, Thakor AS, Hansell JA, Kane AD, Wooding FBP, Cross CM, Herrera EA. Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress. PLoS One. 7(2):e31017, 2012. IF: 3,53 Paper comentado en Science: -may-be.html? This article is among the top 10% most cited PLOS ONE articles.

  • Kane AD, Herrera EA*, Hansell JA, Giussani DA. Statin treatment depresses the fetal defence to acute hypoxia via increasing nitric oxide bioavailability. J Physiol 590.2: 323–334, 2012. IF: 5,04 Paper comentado por Peebles D. J Physiol. 590(8): 1773, 2012.

  • Herrera EA, Camm EJ, Cross CM, Mullender JL, Wooding FBP, Giussani DA. Morphological and Functional Alterations in the Aorta of the Chronically Hypoxic Fetal Rat. J Vasc Res. 49(1):50-58, 2012. IF: 2,90


  • Herrera EA, Ebensperger G, Riquelme R, Díaz M, Reyes V, Torres-Farfan C, Llanos A. Cardiopulmonary response to stepwise oxygenations in newborn sheep from different altitudes. Avances en Ciencias Veterinarias 26 (1-2): 53-63, 2011. 

  • Moraga FA, Reyes RV, Herrera EA, Riquelme RA, Ebensperger G, Pulgar VM, Parer JT, Giussani DA, Llanos AJ. The role of the {alpha}-adrenergic system in femoral vascular reactivity in neonatal llamas and sheep: a comparative study between highland and lowland species. Am J Physiol Regul Integr Comp Physiol. 301(4):R1153-60, 2011. IF: 3,11

  • Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Moraga FA, Parer JT, Giussani DA. Last Word on Point:Counterpoint: High altitude is/is not for the birds! J Appl Physiol. 111(5):1526, 2011. IF: 3,77 Review

  • Scott GR, Meir JU, Hawkes LA, Frappell PB, Milsom WK, Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Moraga FA, Parer JT, Giussani DA. Point: Counterpoint "High Altitude is / is not for the Birds!". J Appl Physiol. 111(5):1515-1518, 2011. IF: 3,77 Review

  • Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Pulgar VM, Serón-Ferré M, Díaz M, Parer JT, Giussani DA, Moraga FA, Riquelme RA. Fetal and postnatal pulmonary circulation in the Alto Andino. Placenta. 32 Suppl 2:S100-3, 2011. IF: 3,29 Review


  • Herrera EA, Riquelme RA, Ebensperger G, Reyes RV, Ulloa CE, Cabello G, Krause BJ, Parer JT, Giussani DA, Llanos AJ. Long term exposure to high altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level. Am J Physiol Regul Integr Comp Physiol. 299(6):R1676-84, 2010. IF: 3,11

  • Thakor AS, Herrera EA, Seron-Ferre M, Giussani DA. Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms. J Pineal Res. 49(4):399-406, 2010. IF: 9,6 Paper comentado por Peebles D. J Physiol. 590(8): 1773, 2012.

  • Camm EJ, Hansell JA, Kane AD, Herrera EA, Lewis C, Wong S, Morrell NW, Giussani DA. Partial contributions of developmental hypoxia and undernutrition to prenatal alterations in somatic growth and cardiovascular structure and function. Am J Obstet Gynecol. 203(5):495.e24-34, 2010. IF: 3,97

  • Herrera EA, Verkerk MM, Derks JB, Giussani DA. Antioxidant treatment alters peripheral vascular dysfunction induced by postnatal glucocorticoid therapy in rats. PLoS One. 5(2):e9250, 2010. IF: 3,53

  • Herrera EA. Professor Giorgio Pardi and his legacy. Reprod Sci. 17(2):101, 2010. Editorial.  IF: 2,23

Capítulos de Libro

  • La creación e implementación de un Comité Institucional de Cuidado y Uso de Animales (CICUA): Experiencia en la Universidad de Chile. Emilio A. Herrera, Pía Ocampos, Tamara Tadich, Alejandra González, Jurij Wacyk, Ricardo Olivares, Ronald Vargas, Rosario Berrios, Madeleine Lamborot, Carla Delporte, Mauricio Budini, Fernanda Schaufler, Cecilia Vergara, Alejandro Escobar, Alfonso Paredes, Cristian G. Torres, Mario Laborda, Héctor Uribe, Patricio Jorquera, Diego Moreno, Silvia Núñez. Capítulo en: “Ética y seguridad en la investigación. Aprendizajes y desafíos”. Pontificia Universidad Católica de Chile ediciones., 2023.

  • Regulation of Animal Research. Emilio A. Herrera. Chapter 33, In: Handbook of Bioethical Decisions. Volume I - Decisions at the Bench. Eds. E. Valdés & JA Lecaros. Springer Nature, 2022 (ISBN978-3-031-29450-1).

  • Fetal Llama Adaptation to Altitude in the Andean Altiplano. Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Serón-Ferré M. Chapter 5, In: Hypoxic Respiratory Failure in the Newborn – From Origins to Clinical Management. Eds. Dakshinamurti S, Abman S, Cheung P-Y, Lakshminrusimha S, McNamara P, Milsom B. CRC Press, Taylor & Francis Group, Boca Raton, Florida, USA, 2021.

  •  Epigenetic programming of cardiovascular disease by perinatal hypoxia and fetal growth restriction. Casanello P, Herrera EA, Krause BJ. In: Hypoxia and Human Diseases, InTech - open science | open minds; Chapter 17; 2016.

  • Realidad en Chile acerca de los Comité Institucional de Cuidado y Uso de Animales de Laboratorio (CICUAL). Herrera EA, Ocampos P. En: X Taller de Bioética en Chile, CONICYT, pp 25-45, 2014.

  • Heart Disease Link to Fetal Hypoxia and Oxidative Stress. Giussani DA, Niu Y, Herrera EA, Richter HG, Camm EJ, Thakor AS, Kane AD, Hansell JA, Brain KJ, Skeffington KJ, Itani N, Wooding FB, Cross CM, Allison BJ. In: Advances in Fetal & Neonatal Physiology; Proceedings of the 40th Anniversary of the Center for Perinatal Biology. Ed. Ducsay, A. & Zhang, L. Springer, New York.  Adv Exp Med Biol. 2014;814:77-87. doi: 10.1007/978-1-4939-1031-1_7.